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Klont (Metronidazole)

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Klont is in a class of drugs called nitroimidazole antimicrobials. This medicine will only help infections caused by bacteria and will not work for the common cold, flu, or other viral infections. It works by stopping the growth of bacteria.

Other names for this medication:
Acuzole, Amotein, Amotrex, Aristogyl, Collazole, Ginkan, Metrazol, Metris, Metrolotion, Metrosil, Metrozole, Molazol, Nidagel, Nidazea, Perilox, Rhodogil, Rosasol, Rosazol, Rosiced, Rozagel, Stomorgyl, Tismazol, Tolbin, Tricozyl, Vagilen, Vandazole, Venogyl, Vertisal, Wingyl

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Also known as: Metronidazole


Metronidazole vaginal is used to treat women with vaginal infections (eg, bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing the bacteria or preventing their growth. However, this medicine will not work for vaginal fungus or yeast infections.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Klont I.V. RTU. Please read with care.

A nurse or other trained health professional will give you this medicine in a hospital. It is given through a needle placed into one of your veins.

Your doctor will give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Detailed Metronidazole dosage information


In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Klont overdose, Klont infusion should be discontinued. Patients should be treated symptomatically.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Klont ER dosage information

Side effects

The most common side effects associated with Klont are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of metronidazole capsules and tablets in the pediatric population, except for the treatment of amebiasis. Safety and efficacy have not been established.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of metronidazole extended-release tablets to treat bacterial vaginosis in teenage females, but should not be used before the start of menstruation.

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Physiological and pharmacological maneuvers were performed to perturb the renin-angiotensin system, including 24-h bilateral nephrectomy and furosemide administration to change renin and adrenalectomy and administration of dexamethasone to alter renin substrate. Immobilized anhydrochymotrypsin as a biospecific affinity adsorbent for the peptides produced by chymotryptic hydrolysis. In spite of this neither the mechanism by which it is produced not its clinical importance are fully defined. Iron and transferrin in the blood serum of the patients with acute cerebral vascular disease. Low prevalence of latex allergy in children with spinal dysraphism in non-latex-free environment. Whole laminin was not detected, whereas laminin fragments of 270, 155, 87, 56, and 14 kDa were detected at a mean total value of approximately 0.5 microgram/ml. Detection of one way blocking in a blocking ELISA, with a pair of mAbs reacting to non-overlapping epitopes, suggested conformational change as the mechanism of blocking. Extraction of phosphorylated sperm specific histone H1 from sea urchin eggs: analysis of phosphopeptide maps. Significant levels of gentamicin were detected in the CSF shortly after injection in the absence of inflammation.

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Randomized prospective study of the impact of three needleless intravenous systems on needlestick injury rates. Regression models show a significant association with introduction of the mother-and-child health passport in 1974 and decreasing fertility of women older than 35 years. The preincubation of cells with arachidonic acid could prevent the inhibition mediated by the reversible phospholipase A2 inhibitor cibacron blue. Prevalence of IgG-antibodies to mumps and measles virus in non-vaccinated children. The importance of identifying and preserving the recurrent laryngeal nerve in the surgical management is highlighted. It was also proved that it does not show toxicity--LD0 and LD50 were higher than the maximal does applied. The viability of the infected cells exposed to (125)I in the presence of 5-FC was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, and the infected cells exposed to (125)I alone served as negative control and 5-FU as positive control. Seroepidemiologic survey of leptospirosis among environmental sanitation workers in an urban locality in the southern region of Brazil. Five chinchillas, tested for comparison, responded similarly to PG-APS. A telephone interview with the parents or child or both was then conducted by using a structured questionnaire.

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Our objective was to examine the accuracy of a 15 MHz ultrasound miniprobe in the pre-operative staging of colorectal cancer by assessing the depth of tumor infiltration and involvement of pericolonic lymph nodes. Maternal education and child health: is there a strong causal relationship?. Even though brachytherapy has been used for many years to treat choroidal tumors, it is not a widespread technique because it requires much organization and operators skills. Factors associated with osteoarthritis of the knee in the first national Health and Nutrition Examination Survey (HANES I). Stability of Penicillium vitale immobilized catalase in continuous decomposition of hydrogen peroxide. After 4 days in a conventional serum-supplemented medium, the cardiomyocytes were incubated for 24 h in synthetic media containing either linoleate and arachidonate (SM6 Medium) or linolenate and eicosapentaenoate (SM3 Medium) as unique source of PUFA. During the moulting periods, which continue to occur in the adult stage, these cells undergo a series of transformations. Further study based on larger population is required to confirm these findings.

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We have used a synthetic neural model to illustrate value-dependent acquisition of a simple foveation response to a visual stimulus. The role of glutathione status in the protection against ischaemic and reperfusion damage: effects of N-acetyl cysteine. What is the current recommended waiting time for performance of a gastrointestinal barium study after endoscopic biopsy of the upper or lower gastrointestinal tract?. Various scoring systems including Ranson, Acute Physiology and Chronic Health Examination (APACHE II), the Bedside Index for Severity in Acute Pancreatitis, and Computed Tomography Severity Index (CTSI) were calculated. On the angiographic demonstration of collateral circulation through the external carotid artery in thrombosis (occlusion) of the internal carotid artery.

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Frequency of a deletion polymorphism in the gene for angiotensin converting enzyme is increased in African-Americans with hypertension. tabacum cv Xanthi cells, and (d) elicit H2O2 accumulation in the cv Xanthi cells. Neuroendocrine function in transgenic male mice with human growth hormone expression. Semisynthetic pyrrolizidine: N-4-phenyl-phenacyl-heliotridanium bromide, a potent non-specific spasmolytic. Seventeen novel analogues, consisting of aliphatic carbamates, alicyclic amides, and heteroaromatic amides, were synthesized. Cell survival before and after DXT treatment was analyzed by phase-contrast microscopy and crystal-violet staining assays. Gonococcal infections caused by penicillinase-producing Neisseria gonorrhoeae (PPNG) isolates have increased in geographic distribution and prevalence. The results of this study suggest a basis for the finding that sudden death is more common in patients with diabetic autonomic neuropathy. Ninety-six patients with CRVO were treated with TPA between May 1986 and December 1992.

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Therefore, it is possible to significantly reduce the systemic absorption of timolol without reducing its ocular absorption by using a low dose of its O-butyryl prodrug. Bisphosphonates, in an adequate dose, reduce the rate of skeletal complications. Blood transfusions and serum hepatitis: use of monochloroacetate as an antibacterial agent in plasma. Evaluation of the Banff criteria for the histological diagnosis of rejection in renal allograft biopsies. Conventional synthetic disease-modifying antirheumatic drugs (DMARDs) showed little or no steroid sparing effects, while biological agents represent a valid therapeutic option in patients with severe and/or relapsing LVV. Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide. US characteristics were compared with histopathologic features and biomarkers. We have shown that azadirachtin, a compound from the neem tree, Azadirachta indica, and selected semi-synthetic derivatives, block the development of the motile male malarial gamete in vitro. Reduction of dopamine release and synthesis by repeated amphetamine treatment: role in behavioral sensitization. Method of endoprosthesis after extensive resection of articular ends of the femur in oncologic patients, and the evaluation of the kinematics of locomotion.

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Anaerobic granular sludge is composed of multispecies microbial aggregates embedded in a matrix of extracellular polymeric substances (EPS). (8) proposed statistical methods to evaluate the treatment effects in animal reproductive toxicology research. Although the patients shared some clinical and angiographic similarities, the older patients had a lower mean visual acuity and were more likely to have diffuse retinal pigment epitheliopathy, bilateral involvement, and secondary choroidal neovascularization than were the younger patients. We now directly show that the SMAD2 pathway can cooperate with the Wnt pathway to induce expression of Siamois much more strongly than the Wnt pathway alone, in normal embryos. The third period, the current period, began in 1994 when the government proposed a new perinatality plan based on a new perception of maternal mortality risk and a come back of the idea of a collective approach to safe birth. Behavior of rat fleas after the death of the host (towards an improvement in the method of counting rat fleas). Here, we demonstrate a microfluidic approach to generate porous carbon particles using inexpensive precursors and show that the size of the particle and pores can be tuned by adjusting the deionized (DI) water content in droplets and preheating temperature. Age-related differences in responses to verapamil have been noted in both intact humans and isolated denervated perfused rat hearts. Separation was carried out on a fused-silica capillary column coupled to a flame ionization detector.

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We present here partial assignments corresponding to five amino acid residues: Leu86, Leu-91, Val-93, Leu-101 and Leu-136. Malignant melanoma of the penis is rare and accounts for only a small percentage of penile carcinomas. Subnormothermic ex vivo liver perfusion is a safe alternative to cold static storage for preserving standard criteria grafts. Subcutaneous injection of the incretin hormone glucagon-like peptide 1 abolishes postprandial glycemia in NIDDM. The clinical and imaging features of venous sinus thrombosis are described. Caesium ions also prevented the hyperpolarization produced by bath-applied acetylcholine but potentiated the responses to vagal stimulation. Masculinizing genes are required for gynoecial abortion, feminizing genes arrest stamen development, and both types also control secondary sexual traits involving morphological characteristics of floral tissues. The role of brown adipose tissue in total energy balance and cold-induced thermogenesis was studied.

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Factor V Leiden and the risk of proximal venous thrombosis after total hip arthroplasty. All these with LUF syndrome had substantial deviation of the BBT graphs. Inhibition by hydroxyl radicals of calcitonin gene-related peptide-mediated neurogenic vasorelaxation in isolated canine lingual artery. Management of chronic alveolar hypoventilation by nasal ventilation. The aim of this study was to provide evidence-based recommendations for omega-3 supplementation during pregnancy through a systematic review of level-1 data published on this topic. Comparative evaluation of surgical wound healing in laryngeal cancer patients after gamma and electron therapy. Trunk Extensor, Flexor and Lateral Flexor Endurance Time in Sedentary Workers Aged 20-49 Years. Principles underlying the assessment of ventricular and myocardial work and power capacity.

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Laser scanning tomography has been shown to be an accurate and reliable method for the assessment of the three-dimensional optic disc topography. Use of microfibrillar collagen hemostat (Avitene) and thrombin to achieve hemostasis after median sternotomy. Furthermore, real methodological proposals are made for general cancer prevention, suppression of metastasis, and reduction of recurrences, and the concept of a combined therapy is developed. Diagnosis and treatment of nephrolithiasis: current perspectives. This prospective study was undertaken to assess the biocompatibility of different intraocular implants and to determine factors influencing cellular reactions on intraocular lenses (IOLs). The first patient improved clinically after two days of altered therapy, the second after 10 days.

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alpha B-crystallin and hsp25 in neonatal cardiac cells--differences in cellular localization under stress conditions. Hopefully, it is the questionable drug practices that will be ended, rather than simply the convenient access physicians have long had both to established and newly approved drug products. These advances warrant implementation of an update and review process, something that is best done under the auspices of the national and international cardiology societies. An obvious anti-aging effect was found by Bushen Shengxue drug to treat Wistar rats. Temporary pacing (for prolonged asystole) was required in only two patients, both of whom had also undergone bypass surgery. Contributions to the pathogenesis and treatment of tinnitus or ringing ears.

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In this review authors look back at the above mentioned techniques development of bowel connection and reparation regarding of oncoming experiments focused on ways of bowel anastomosis quality improvement. Effects of bile acids on colon carcinogenesis in rats treated with carcinogens. Linkage disequilibrium between a SacI restriction fragment length polymorphism and two galactosemia mutations. It is concluded that, with the possibilities that are offered by the new framework of standards, it will be possible to implement an Occupational Health Information System which will allow for determining priorities and reaching the objectives that have been set. Antibodies to the 280-kd coated pit protein, target of teratogenic antibodies, produce alterations in the traffic of internalized proteins. Study of the cervical portion of the facial vein of fetuses, newborns and children. In this study of 41 patients with progressive juvenile chronic arthritis (JCA), born between 1946 and 1970, it was noticed that 14 were born in the same year (1963). Here, we determine whether or not any sex-specific tra-2 products are expressed that may account for either of these sex-specific activities. Cell interactions and endoderm differentiation in cultured mouse embryos.

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Here, we have expanded insight into the regulatory activity of the GAS small RNA FasX. It is stressed that enucleation is the treatment of choice for leiomyoma and an extensive gastrectomy for cases of leiomyosarcoma. We assume that this was a rare case of left ventricular aneurysm without prior myocardial infarction, the etiology which might related to the anomalous coronary artery. The proposed method has been compared with standard methods like superglue fuming, small particle reagent and gentian violet (for adhesive tapes). This calibration gave satisfactory results both in the linearity of the characteristic and in the performance of the device.

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Seven days post-inoculation, when the tumor had grown to 8.0-10.0 mm in diameter, 120 tumor-bearing mice were randomly divided into three groups: (1) sham-irradiated controls, (2) mice receiving 200 cGy five times a week for 6 weeks, and (3) mice receiving 800 cGy once a week for 4 weeks. Informational theoretical determination of the necessary number of repeated measurements in tests of quality of dosage forms. Compartmentalization of mammalian proteins produced in Escherichia coli. Cytogenetic studies of stainless steel welders using the tungsten inert gas and metal inert gas methods for welding. Various methods measuring physical activity ( is diflucan safe during breastfeeding PA) that have been used so far in older population are described. During operation, the fibula flap could be cut in appropriate length. A brief account is given of the reasons underlying the choice of this approach. Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A. The toxicity of rat large granular lymphocyte tumor cells and their cytoplasmic granules for rodent and African trypanosomes. Dependence of electrical activity of the amygdaloid complex on level of motivation and emotional state of the dog.

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Due to different MR signal characteristics, the etiology of macrodactyly may be recognized, e.g., vascular and/or fatty versus neurofibromatosis, etc. Changes in the sialic acid content in the blood serum of calves with bronchopneumonia following treatment. The locomotor stimulation induced by MK-801 at 0.3 mg/kg was significantly inhibited by the D2 dopamine receptor antagonist raclopride (0.1-0.3 mg/kg, SC) and by the D1 receptor antagonist SCH 23390 (0.04 mg/kg, SC). The kallikrein-kinin system: its significance in circulatory failure and the effect of angiotensin I-converting enzyme inhibitors. At the primary repair stage, the sheath interposing graft achieved more significant gliding excursion than the groups of direct sheath closure (P less than 0.01) and partial sheath excision (P less than 0.001), and no difference was found between the latter two groups (P greater than 0.05). While extracranial metastases of intracranial germinomas via shunts are probably rare, their occurrence, as exemplified by this case, argues for including protective filters in the shunts. The reagents used were 1 M CH3SH-0.43 M NaOH, 1 M NaBH4-0.1 M NaOH, 1 M CH3NH2-0.1 M NaOH, and 1 M Na2SO3-0.1 M NaOH. PEP changes due to a decrease of preload and increase of afterload of the fetal heart, the relative better oxygenation of the fetal scalp during uterine contractions and decelerations due to a redistribution of circulating blood volume caused by a selective peripheral vasoconstriction.

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We sought to determine predictors of IPN progression to pulmonary metastasis and develop a tool for individualized risk stratification of patients who present with IPN on preoperative chest imaging in the setting of localized or locally advanced renal cell carcinoma. Synthesis and effects of two peptide fragments of thymopoietin II on E-rosette forming cells in the uremic state. Boronate affinity materials, as unique sorbents, have maximum dose of imipramine emerged as important media for the selective separation and molecular recognition of cis-diol-containing compounds. Cholestatic liver disease is associated with clinical and experimental findings consistent with increased opioidergic neuromodulation, increased plasma total opioid activity, and elevated plasma enkephalin concentrations. Understanding and optimising the packing density of perylene bisimide layers on CVD-grown graphene. Two kinetically distinct esterases were similarly detected in liver microsomes from mouse, hamster, guinea pig, rabbit, cat, cynomolgus monkey, and human, but only the high-affinity enzyme was detectable in dog liver microsomes. The emotional states and cognitive abilities of animals have been studied but will become an increasingly important component of behavior research into animal welfare in the future. Calculated on a basis of a 2 year period, the cost of artificial feeding amounted to 310 U.S.

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Estradiol and oxytocin increased, whereas progesterone decreased, CX-43 protein levels and morphological gap junctions. The latter may be filled uniformly with glycoprotein or glycoprotein may form a thin peripheral coat about centrally located lactoferrin and lysozyme. We have proposed a molecular model of susceptibility to Insulin-Dependent Diabetes Mellitus (IDDM) based on the proportional expression at the cell surface of the following susceptible (S-S) HLA-DQ heterodimere composed of a chain DQ alpha Arg 52 positive (S) and a chain HLA-DQ beta Asp 57 negative (S). Endogenous protein phosphorylation in rat brain mitochondria: occurrence of a novel ATP-dependent form of the autophosphorylated enzyme succinyl-CoA synthetase. The etiology of gastric carcinoma was investigated by the family study method. On the other hand, at least half stated that job-related factors would influence them to leave their present positions. This consists of 9104 Swedish Interactive Thresholding Algorithm Standard 24-2 VFs. Fatigue was usual in males and several factors were associated with the fatigue. Pathology of the senescent heart: anatomic observations on 237 autopsy studies of patients 90 to 105 years old.

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Biochemical characterization of three stimulatory GTP-binding proteins. Surgical treatment of rheumatoid lesions of the ankle joint in children. Various alterations including thickening, degradation and neosynthesis were found in the bladder BM of one rat with invasive TCC. Multiple PEX genes are required for proper subcellular distribution and stability of Pex5p, the PTS1 receptor: evidence that PTS1 protein import is mediated by a cycling receptor. We demonstrate the current insight on indications, contraindications and the technique of renal biopsy.

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Occupational prometrium 200 mg ivf asthma in tomato growers following an outbreak of the fungus Verticillium albo-atrum in the crop. A three year clinical review of the impact of angiotensin converting enzyme inhibitors on the intra hospital mortality of congestive heart failure in Nigerians. Traumatic rupture of the thoracic aorta: the diagnostic challenge. Recombinant, purified VAT-1 stimulated PS transport into mitochondria and depletion of VAT-1 from Xenopus cytosol with specific antibodies led to a reduction of transport. If the number of females is constant, this success depends on the ratio between the mutant and wild-type males. We managed a patient with pneumothorax caused by a large bulla by so called modified Naclerio-Langer method under thoracoscopic procedure. Inhibitory action of intravenously administered ammonium acetate on the motility of the rumen in sheep. L-Dopa (50 mg/kg, sc) and benserazide (12.5 mg/kg, ip) plus L-Dopa (50 mg/kg,sc) significantly increased chloroquine (5 mg/kg, ip)-induced locomotion. While poorly studied to date, arctic food webs are commonly assumed to be simple in structure, with few links per species.

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However, cGMP levels were synergistically increased by the BK-stimulated EDNO when EC were co-cultured with SMC. Plasma concentrations of cilastatin and N-acetylcilastatin at selected time intervals and biliary and urinary recoveries of cilastatin and N-acetylcilastatin following an ventolin inhaler dosage form intravenous dose of 10 mg/kg cilastatin are presented. Two non-overlapping cosmid contigs were identified which contain STP-like sequences. Both all-trans and 9-cis RA inhibited virus replication in HIV-1 IIIB-infected monocytoid cells, in the presence and absence of the co-stimulatory agent phorbol myristate acetate (PMA). These findings support the hypothesis that the family is a significant influence on physical activity.

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The effects of including corrections for interphase death are demonstrated. We hypothesized that the biofilm formation heterogeneity observed was rather associated with biofilm matrix composition than with cells themselves. The cause of the different signs and symptoms in both types of neurontin renal dose lesion are discussed. The importance of these findings to tumour growth in vivo is discussed. The increase in Vdss with dose indicated an increase in tissue-to-plasma concentration ratio, which may be attributed to the increase in distribution of unbound drug from plasma to tissues subsequent to non-linear plasma protein binding. Multicellularity in the cellular slime mold Dictyostelium discoideum is achieved by the expression of two types of cell-cell adhesion sites. Anti-Tac(Fv)-PE40 is a recombinant single-chain immunotoxin in which the variable heavy and light domains of the anti-IL2 receptor antibody, anti-Tac, are connected to each other by a peptide linker and then fused to PE40, a truncated form of Pseudomonas exotoxin (PE). Bevacizumab Wins Cost-Effectiveness Contest in First-Line Metastatic Colorectal Cancer.

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Localization of autoepitopes on the PCM-1 autoantigen using scleroderma sera with autoantibodies against the centrosome. The related compound, pteroyl-S-methylhomocysteine sulfone, which cannot undergo enzyme-mediated activation, was also investigated. Effects of soman poisoning on hematology and coagulation parameters and serum biochemistry in rabbits. Prenatal antagonism of stress by naltrexone administration: early and long-lasting effects on emotional behaviors in mice. To verify the clinical applicability of a modified classification system in distractive-extension cervical spine injury that reflects the degrees of soft tissue damage and spinal cord injury while complementing previous Allen classification and subaxial cervical spine injury classification (SLIC) system. Ketosis resistant diabetes of the young: a profile of its exocrine and endocrine pancreatic dysfunction. In a minimally invasive fashion, hGluc secreted by MSCs into circulation as a reporter for cancer presence, was assayed daily dose of motrin to probe whether MSCs co-localize with and persist in cancerous tissue.

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