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Glimestar (Glimepiride)

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Glimestar tells your pancreas to increase the amount of insulin it produces in your body. Insulin works to lower your blood sugar. Glimestar lowers your blood sugar in about 2 to 3 hours after you take the medication. This is why it is important to take the medication with your largest meal of the day.

Other names for this medication:
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Also known as: Glimepiride


Glimestar (glimepiride) is an oral diabetes medicine that helps control blood sugar levels.

Glimestar is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. This medicine is not for treating type 1 diabetes.

Insulin or other diabetes medicines are sometimes used in combination with Glimestar if needed.


Usual Adult Dose for Diabetes Type 2:

Initial dose: 1 to 2 mg orally once a day Maintenance dose: Increase in 1 or 2 mg increments no more frequently than every 1 to 2 weeks based on glycemic response Maximum dose: 8 mg per day Comments: -Administer with breakfast or first main meal of the day. -In patients who are at increased risk for hypoglycemia, start with 1 mg orally once a day and titrate slowly. -When patients are being transferred to this drug from a longer half-life sulfonylurea, monitor 1 to 2 weeks for overlapping drug effect. Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.

Usual Geriatric Dose for Diabetes Type 2:

Initial dose: 1 mg orally once a day; titrate slowly and monitor closely

Usual Pediatric Dose for Diabetes Type 2:

Not recommended because of adverse effects on body weight and hypoglycemia.

Detailed Glimestar dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An Glimestar overdose can cause life-threatening hypoglycemia.

Symptoms of severe hypoglycemia include extreme weakness, confusion, tremors, sweating, fast heart rate, trouble speaking, nausea, vomiting, rapid breathing, fainting, and seizure (convulsions).


Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Glimestar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.

Avoid exposure to sunlight or tanning beds. Glimepiride can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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