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Gitox (Losartan)

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Gitox is a hypertension treatment. Research suggests that the medication is safe and effective for most people. People may experience mild side effects, such as dizziness, in the early stages of treatment. People who experience severe or persistent side effects should contact their doctor right away.

Other names for this medication:
Cardoplus, Cardzaar, Corodin, Corus, Cozaarex, Czartan, Enromic, Gitox, Hilos, Hizaar, Hypozar, Insaar, Lepitrin, Loben, Logika, Loplac, Losadel, Losamet, Losan, Losap, Losaprex, Losarb, Losartas, Losartax, Losatan, Losazid, Losazide, Lostat, Lotim, Lozatan, Maxartan, Myotan, Niten, Ozarium, Psycholanz, Ranlozar, Rasoltan, Sarilen, Sarlo, Sartens, Satoren, Tanlozid, Tarnasol

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Also known as: Losartan


Gitox (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Gitox is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Gitox is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Gitox 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Gitox 25 mg, Gitox 50 mg, and Gitox 100 mg may also contain carnauba wax.


Take Gitox tablets orally with or without food. Do not crush or chew it. Take Gitox once or twice a day at the same time. If you want to achieve most effective results do not stop taking Gitox suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Gitox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Gitox as soon as possible.

In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with Gitox. Correct volume or salt depletion prior to administration of Gitox.

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MT cells show strong suppression between opposite directions of motion. Externally applied pressure can transduce from the middle ear through the perilymph, cerebrospinal fluid, and the recently discovered glymphatic pathway to the extracellular matrix space, and finally to the paravenular space. High-level expression of bovine beta-lactoglobulin in Pichia pastoris and characterization of its physical properties. By that time it is estimated that a total of about 8000 strokes, 12,000 coronary heart disease events and 23,000 cardiovascular events in total will have occurred. Primary aims of the present study included evaluation of: (a) the association of this comorbidity with decrements in health-related quality of life (HRQOL) and (b) the importance of CSA as a predictive factor for this comorbidity in a general population sample. The secretory form of alpha-1,4-glucosidase remained unchanged while the lysosomal form of the enzyme and also cathepsin D increased in the cytosol of both caput and cauda epididymis. harzianum were able to improve substantially the antifungal ability of a biocontrol strain of Enterobacter cloacae. Chromatin boundary elements (CBEs) are widely distributed in the genome and mediate formation of chromatin loops, but their roles in gene regulation remain poorly understood.

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Binding of the galactose-specific Pseudomonas aeruginosa lectin, PA-I, to glycosphingolipids and other glycoconjugates. The Ammann filter test is a subjective method of differentiating functional amblyopia from the organic type. Association between myotonic dystrophy and primary hyperparathyroidism. Low-dimensional dynamic self-organization in delta-sleep: effect of partial sleep deprivation. Exposure of children to chlorinated dibenzodioxins and chlorinated dibenzofurans via breast-feeding has been well-documented in industrialized countries. Urinary alpha 2-macroglobulin excretion rate in type 2 diabetic patients.

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Variations in the cellular site (cytoplasm, cell membrane, and nucleus), the distribution (particulate or homogeneous), and the quantity (little or much) of Rous viral antigens were seen. Levels of glutamic acid decarboxylase (GAD), gamma amino butyric acid transaminase (GABA-T), glutamic acid dehydrogenase (GLDH) and proteins in cerebrospinal fluid of certain neurological disorders. Ejaculate of cooks was diluted by the Wishart and Davtjan diluents at a ratio of 1 : 1 and stored at a temperature of 4 degrees C during 2, 24, 48 and 72 hours before insemination of laying hens by the doses of 25, 50, 75, 100 and 150. Rapid AOA dynamics are encountered in II or III degree chronic congestive circulatory insufficiency. Seven patients were treated with pressure dressings, antibiotics, and immobilization. To help determine optimal strategies for treating suicidal adolescents, the authors studied family predictors of compliance with recommended psychotropic medication monitoring, individual therapy, and parent guidance/family therapy sessions. The investigation of the neuronal activity in the monkey cerebral cortex during the delayed spatial choice performance allowed us to develop the hypothesis about two neuronal networks supporting the operative memory. Early identification of treatment failures in short-term psychotherapy. Bounce was eliminated by coupling the striker to a simple hydraulic-pneumatic damping device.

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Simultaneous to intravenous injection of 265 MBq of 11C-TYR, dynamic PET acquisition was started and continued for 50 min. Influence of embryo culture medium on incidence of ectopic pregnancy in in vitro fertilization. The following day CER, as measured by interruption of drinking in response to CS presentation, was recorded. Only the last test was able to detect an antigenic relationship between the hemagglutinin of this isolate and an H3 subtype influenza virus. Pannexins (Panx) are proteins with a similar membrane topology to connexins, the integral membrane protein of gap junctions.

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Persistence of parvovirus B19 DNA in testis of patients with testicular germ cell tumours. gondii oocysts and an additional four animals were used as non-inoculated controls. Due to the absence of any navigational impairment, data suggest that prenatal exposure to oxazepam exerts long-term influence on adult learning capacities primarily through interaction with brain systems located outside the hippocampus. In response to: Comparison of temporal fascia and cartilage grafts in pediatric tympanoplasties. Other possible mechanisms and implications of this observation are discussed. The results indicate that a great majority of the patients and the parents easily accept the self-testing method and regard it as a valuable tool in the management of the disease. The t 1/2 of chloramphenicol showed a significant correlation with serum albumin and prothrombin time index. Fluconazole treatment for vulvovaginal candidiasis during pregnancy. In the first year following BMT for CML, PCR used to detect the leukemia-specific BCR/ABL message frequently reveals subclinical levels of persisting leukemia.

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Oral altretamine is a useful agent in patients-who relapse after previously responsive ovarian cancer. The results of suprathreshold speech recognition tasks show substantial variability in performance but this is no greater than that obtained from implant users with no malformation. Although gliomas and glial cells contained different species of tyrosyl phosphoproteins before treatment, they expressed similar kinds of tyrosyl phosphoproteins in response to insulin. Statistically established criteria for its application have hitherto been lacking. In addition, the gamma(c) or another interactive subunit may influence IL-13 binding to its receptor complex. Erythrocytosis in a 4 year-old child: diagnostic, prognostic, therapeutical problems. Implantation of permanent deep electrodes by the Talairach stereotaxic method. It was greatest in soleus-derived myotubes, least in TA-derived myotubes, and intermediate in diaphragm-derived myotubes.

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However, it was shown to be more potent as analgesic than antiinflammatory in the present model. spectroscopy to monitor alginate biosynthesis in mucoid Pseudomonas aeruginosa. It is concluded that RA does not induce biochemical differentiation of the neuroblastoma into mature cells even when there are extensive morphological changes and suppression of growth rate. Incidence of arrhythmia with central venous catheter insertion and exchange. The basic patterns of physical development, periods of postnatal ontogenesis and somatometric characterization described above help to objectively monitor the physical fitness of rhesus-monkeys, to adequately select animals identical in terms of their biological age, and to reliably plan long-term studies on this primate species.

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The RIS can rapidly infuse warm blood, crystalloid, or colloid at rates up to 1.5 L/min, thereby limiting the commonly associated hypotension, hypothermia, and coagulopathies. The main dietary source of omega-3 polyunsaturated fatty acids (n-3 PUFA) is fish, which contains eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Rheumatologic clinical and laboratory evaluations were the following: Bath AS Disease Activity Index, Bath AS Metrology Index, Bath AS Functional Index, C-reactive protein and erythrocyte sedimentation rate for AS and Disease Activity Score 28 joints, and C-reactive protein and erythrocyte sedimentation rate for patients with RA. We reveal the double-reduction landscape in tetraploid potato, clearly showing that this phenomenon increases with distance from the centromeres. Compound synapses within the GABAergic innervation of the auditory inner hair cells in the adolescent mouse. This case represents a diagnostic pitfall, since both entities were unrelated. Neurobiology of psychotropic drugs: modes of action and therapeutic efficacy. The simplest approach so far to generate human PSC lines is through reprogramming of somatic cells from an individual by defined factors, referred to simply as reprogramming.

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Clinical and roentgenographic findings in a patient with primordial microcephalic dwarfism type Caroline Crachami. Moreover, the maturation of unmyelinated fibers of the phrenic nerve has been studied with the electrom microscope. The Co3O4/NGF electrode shows an enhanced charge-storage performance, attributed to the cost of bystolic 5 mg 3D hierarchical structure and the synergistic effect of Co3O4 and NGF. Direct milk excretion of Campylobacter jejuni in a dairy cow causing cases of human enteritis. In vivo effect of OPC15161, a superoxide scavenger, on anti-Thy1 nephritis.

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More than 30 preoperative and operative parameters were evaluated, and all complications were recorded. Mesocortical dopamine neurons: rapid transmitter turnover compared to other brain catecholamine systems. Ever since then serious efforts have been made to develop prophylactic measures to combat the disease without much success. A retrospective postal survey was carried out, on an unselected series of patients in Leicestershire, one to two years after transurethral resection. Between the complications are the appearance of gastrointestinal neoplasms. Pretreatment with labetalol 10(-4) mol/l inhibited the transient increase in perfusion pressure induced by norepinephrine 3 x 10(-5) mol/l. In four tumors with LOH on 17p, the chromosomal breakpoint was located between D17S953 and D17S805.

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These findings suggest that the amnestic effects of DZP can be blocked by the administration of SP and that the amino acid sequence responsible for this effect may be encoded by its N-terminal part. Application of Spanish quality instruments about organ donation and tranplants validated in pilot hospitals in normal plavix dosage Santa Catarina. Combined immunocorrection with the agents tactivin and leukinferon possesses a high potential of an immunobiological effect and can be recommended for correction of severe secondary immunodeficiency in patients with generalized peritonitis. As a striking result, the functional modifications induced by Thr152----Ile activate the adenylate cyclase in vitro much more efficiently than those induced by Gly19----Val. Farms in areas containing less than one herd/km2 were 1.5 times more likely to have a negative or weakly positive BHV-1 status than herds in areas with more than three herds/km2. The nutritional habits of 114 patients with ulcerative colitis were investigated by means of questionnaires and compared with a control group of 114 persons matched to age, sex and social status. Parameters analyzed included age, sex, American Spinal Injury Association Impairment Scale on admission, mechanism of injury, presenting symptoms, time of onset, and risk factors. 99mTc-tetrofosmin myocardial SPECT during vasodilation with dipyridamole for detecting coronary artery disease.

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Flurazepam and its major metabolites were analysed in blood and urine. The simultaneous presence of different basic type 1 and acidic type 2 RIPs in the same plant and in the same tissue is described here for the first time and opens a new door in research into RIPs. A switch in prescribing, from drugs with a high number of deaths per million prescriptions to drugs with a low number, could reduce the numbers of deaths from overdose. We propose a new approach, sparse meta-analysis (SMA), in which variable selection for meta-analysis is based solely on summary statistics and the effect sizes of each covariate are allowed to vary among studies. The complexity of this method is lower than that of any other two dimensional minimum Hausdorff algorithm. A conventional ELISA kit identified 10 patients with type 1 diabetes and one patient with type 2 diabetes as glutamic acid decarboxylase autoantibody positive, whereas 15 patients with type 1 diabetes and six patients with type 2 diabetes were identified as glutamic acid decarboxylase autoantibody positive using immune complex transfer enzyme immunoassay. Endogenous glucocorticoids, as end-effectors of the hypothalamo-pituitary-adrenal axis, inhibit the immune and inflammatory responses and are used as immunosuppressive drugs in many inflammatory, autoimmune and allergic diseases. A new polyazine-bridged RuRuPt trimetallic supramolecular architecture emulates the photophysical properties of the previously reported Ru2RuPt tetrametallic architecture that exhibits photoinduced charge separation. Fluctuation analysis of motor protein movement and single enzyme kinetics. Tests for choice of treatment regimens (1.3, 1.5, 1.8 atm.) were the dynamics of subjective and objective clinical signs, indices of the peripheral hemodynamics and thermoregulation.

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Bone mineral density had the strongest relationship with age in postmenopausal women. In patients with a rather shallow gradient of light sensitivity in the area between the intact visual field and the scotoma, a fairly good recovery was obtained, whereas in patients with a steeper gradient the enlargement of the visual field was small. Histopathology of Incontinence-Associated Skin Lesions: Inner Tissue Damage Due to Invasion of Proteolytic Enzymes and Bacteria in Macerated Rat Skin. When a keratometer is held closer to the astigmatic cornea, the elliptical image will appear more circular, particularly for larger degrees of astigmatism. The use of glyceryl trinitrate in inexaminable patients with anal fissure. A novel form of synaptic plasticity in field CA3 of hippocampus requires GPER1 activation and BDNF release. Providing a successful course away from the host institution requires a great deal of planning by the educator.

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Levels of agKS and HA in serum from various blood vessels were measured before and 5 h after the injury. Alterations in cytoskeletal functions are permethrin introduced by the administration of microfilamentous and microtubular altering agents such as cytochalasin, colchicine, or EDTA. A new method to estimate within-species gene genealogies was used to establish linkages among individuals associated with the Florida dental human immunodeficiency virus transmission case. Arterial compliance, systolic pressure and heart rate in elderly women at rest and on exercise. Update: alcohol-related traffic fatalities--United States, 1982-1993. The effects of coaching on salivary cortisol stress marker in mothers with young children, a randomized controlled trial. This finding is compatible with studies that showed that G6Pase enzyme activity increases during liver regeneration. The synthesis of polysaccharide was dependent not only on the availability of excess carbon, but also on growth rate. We also show that mutation of key residues at the repeat level abolishes phase behaviour or encodes an orthogonal transition. Reliability of a problem-classification index for well mothers and children in community health nursing.

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Frequency of ST-segment depression produced by mental stress in stable angina pectoris from coronary artery disease. Disseminated intravascular coagulation in association with congenital neuroblastoma. Antibodies to p24 and gp120 were assessed by enzyme-linked immunosorbent assay. All neurographic parameters were obtained by means of simultaneous recording with surface and concentric needle electrodes and compared with one another. This strain may be used as a bacterial preparation for the regulation of intestinal microbiocenosis. Changes in fatty acid compositions of mitochondria during embryonic development. Protecting hospital employees and visitors from aerosolized ribavirin. Animals were repeatedly trained to retrieve food rewards from three arms, until a criterion level of performance was reached. Recently developed methods enable the direct and scalable identification of the signaling pathways capable of driving resistance in specific contexts.

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Determination of cellular DNA content in the diagnosis and prognosis of mesenchymal tumors. Combined single day 14C-triolein breath test and PABA test in the diagnosis of malabsorption. Sensitization to fluorine and manganese compounds and the state of the oral cavity in workers in the electric pipe welding industry. Thallium-201 single photon emission computed tomography in the evaluation of thymic carcinoma. As an adjunct to cancer chemotherapy, we had succeeded in creating the methionine depletion in vivo, using the technique of total parenteral nutrition (TPN) by infusing an amino acid solution devoid of methionine and cysteine, as sole nitrogen source (Met-deplet.

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