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Diamin (Imipramine)
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Diamin

Diamin works by inhibiting the reuptake of certain neurotransmitters in the brain, including acetylcholine, dopamine, norepinephrine, and serotonin. It also acts on certain other receptors, such as H1 receptors for histamine. Diamin usually is administered orally but may be given by intramuscular injection.

Other names for this medication:
Alzoset, Antidep, Antipres, Anxitab, Depforte, Depik, Depnil, Depof, Depranil, Deprid, Depsan, Depsin, Depsol, Depsolam, Depsonil, Diamin, Diazariv, Elamin, Eldep, Elidep, Endopax, Estidep, Finezol, Imidiaz, Imikon, Imilor, Iminza, Imipam, Imipra, Imipramine, Imodep, Impramine, Impranit, Imprax, Imprim, Imprin, Karthin, Lastinem, Libomin, Microdep, Nimipose, Normadep, Prazep, Talendep, Trydep

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Also known as: Imipramine

Description

Imipramine is used to treat depression. It belongs to a group of medicines known as tricyclic antidepressants (TCA). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain.

Imipramine tablets are also used to treat enuresis (bedwetting) in children.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain imipramine. It may not be specific to Diamin-PM. Please read with care.

Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (capsules): For depression: Adults—At first, 75 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day, unless you are in the hospital. Some hospitalized patients may need higher doses. Teenagers and older adults—At first, 25 to 50 mg per day using the tablets. Your doctor may adjust your dose as needed and switch you to the capsule form. However, the dose is usually not more than 100 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): For depression: Adults—At first, 75 milligrams (mg) per day. Your doctor may adjust your dose as needed. However the dose is usually not more than 200 mg per day. Some hospitalized patients may need higher doses. Teenagers and older adults—30 to 40 mg per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 100 mg per day. Children—Use and dose must be determined by your doctor. For enuresis (bedwetting): Children 6 years of age and older—At first, 25 milligrams (mg) once a day, taken 1 hour before bedtime. Your doctor may adjust the dose as needed. Children younger than 6 years of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Diamin can be fatal.

Overdose symptoms may include irregular heartbeats, feeling like you might pass out, seizures, or coma.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Diamin-PM dosage information

Side effects

The most common side effects associated with Diamin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Plasma, red blood cell, total blood, and extracellular fluid volumes in healthy horse foals during growth. Hyponatremia and the syndrome of inappropriate antidiuretic hormone secretion (SIADH) have been associated with several psychotropic drugs e.g., carbamazepine, neuroleptics, tricyclic antidepressants and more recently selective serotonin reuptake inhibiting (SSRI) antidepressants. For this purpose nano-CaP coatings were deposited on cylindrical screw-type (St) implants and implanted bilaterally into the iliac crest of goats for 6weeks. Median age was 80 years (range: 9-95), 11 patients were male, 9 female. This Raman signal is exclusively from the surface-bound complexes with great sensitivity to the binding and orientation of the DOPA attached to the TiO(2) surface. Mechanism of fragmentation of urinary stones by underwater shock wave. Serum RBP4 at 11-13 weeks was measured in 480 singleton pregnancies, including 240 with normal outcome, 60 that subsequently developed preeclampsia (PE), 60 that developed gestational diabetes mellitus (GDM), 60 that delivered large for gestational age (LGA) neonates and 60 that delivered small (SGA) neonates. Federal research funding received from the Canadian Institutes of Health Research and National Institutes of Health was also obtained.

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Peripheral artery disease accounts for more than 400 000 hospitalizations in the USA and results in symptoms ranging from claudication to gangrene. We describe the patients, the clinical course and review the literature pertinent to such cases. He discusses especially the problem of vectors, diagnosis, vaccine and treatment, taking into account the 1982-1987 National Campaign for Animal Rabies Control. The presurgical diagnosis of the tumors as prolactinomas was based on the findings of hyperprolactinemia and radiographic abnormalities, and was confirmed by the electron microscopic features of the specimens as well as by immunocytochemical staining for PRL. Retrospective coronal and sagittal multiplanar reconstructions clearly demonstrated the complex anatomy of the malformation. Quality circles--a summation for inservice educators: using circles to increase staff nurse participation in problem solving. This study assesses the effectiveness of a one-year continuing medical education/continuing professional development course for general practitioners, regarding the improvement in knowledge of ARIA and GINA guidelines and compliance with them in asthma management.

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The economic effects of screening for obstructive airway disease: an economic analysis of the DIMCA program. Maximal cytokine-mediated induction was not observed in the presence of protein synthesis inhibitor cycloheximide, suggesting additional regulatory factors play an important role. Ascorbate (15 mM) added to soluble lens proteins prior to photoirradiation can prevent some of these changes. A comparison of unicompartmental knee replacement with total knee replacement. In the multiple regression analysis, HOMA-IR was independently associated with troponin T elevation.

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